Scientific Tree invites all the Molecular Biology professionals and people interested in Microbiology profession across the nations to submit their Abstracts before the deadline ends. Kindly submit your abstract. There are altogether 23 sessions on Cell Biology profession. Chose your calling and please submit your abstract relevant to the conference or session
Cancer is an abnormal growth of cells the cause of imbalance in cell proliferation and death breaking-through the normal physiological checks and balances system and the ultimate cause of which are one or more of a variety of gene alterations.
These alterations can be structural such as mutations, insertions, deletions, amplifications, fusions and translocations, or functional. Approaches to cancer gene therapy include three strategies: the insertion of a normal gene into cancer cells to replace a mutated gene, genetic modification to silence a mutated gene, and genetic approaches to directly kill the cancer cells.
This session discusses multiple clinical trials using gene and cell-based approaches that are undertaken in Phase I through Phase III testing in patients with a variety of different types of cancer.
Tissue engineering is a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. Tissue engineering involves the use of a scaffold for the formation of new viable tissue for a medical purpose.
While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own. Tissue engineering is nothing but regenerative medicine which incorporates research on self-healing, where the body uses its own systems, sometimes with help foreign biological material to recreate cells and rebuild tissues and organs.
The terms “tissue engineering” and “regenerative medicine” have become largely interchangeable, as the field hopes to focus on cures instead of treatments for complex, often chronic, diseases. This session discusses more about tissue engineering and how it helps cure diseases.
Cells hold the biological equipment necessary to keep an organism alive and successful. According to cell science, cells are the fundamental unit of structure and function in all living organisms. All cells possess hereditary information necessary for regulating cell functions and for transmitting information to the next generation of cells. Living things are either unicellular or multicellular, for instance human being. Cell science has developed a lot dealing with life-threatening diseases. This session discusses the latest research that is going on in the world, technologies and trends that push cell science on the threshold of new discoveries to benefit humankind.
Each country in the world has their own regulatory systems in place with regards to human cells, tissues, and cellular and tissue-based products intended for implantation, transplantation, infusion or transfer into a human recipient, including hematopoietic stem cells.
Every day stem cell products are transported around the world as part of life saving therapies for patients. In view of this to control abuse of such life saving therapies, we need regulations to manage, monitor stem cells and life-saving therapies. These regulations are determined by each individual import and export country. As products are collected and transported across international lines additional regulations should be in place.
Each country has its own local, regional and national regulations on the collection, manufacturing and distribution of cellular therapy products. This session discusses further what regulations needs with regards to stem cells etc.
An international team of scientists has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic mechanisms that drive AGS and test strategies to inhibit the condition using existing drugs. This novel stem cell-derived model created of inflammatory neurological disorder brain-in-a-dish approach also showed two existing HIV drugs may be effective in rescuing mutated cells. This session further discusses more about such novel stem cell technologies such as how novel stem cell technology leads to better spinal cord repair etc.
Nanotechnology is an engineering of functional systems at the molecular scale. It manipulates matter on an atomic, molecular, and supramolecular scale. Nanotechnology is defined as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers. In its original sense, nanotechnology refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products. This session discusses how nanotechnology is applied to cell science and molecular biology.
Cell Signaling Technology, Inc. (CST) was founded in 1999 by scientists in the Cell Signaling group at New England Biolabs. CST develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related regents used to study the cell signaling pathways that impact human health.
It has developed an extensive library of scientific resources to support research and to help educate students and research scientists. One can explore these research tools and can also contribute towards tools or ways where we can help improve our scientific resources a great deal. Scientists at CST curates and maintains PhosphoSitePlus, a web-based bioinformatics resource that details post-translational modifications (PTMs) in human, mouse and rat proteins.
The types of PTMs curated include phosphorylation, acetylation, methylation, ubiquitylation, glycosylation, etc. This CST is a freely accessible, online resource funded in part through grant support from NIH, and most recently through the NIH BD2K initiative.
The Current Research in Cell & Molecular Biology explores several research studies that are going such as protein folding and protein secondary structure; the development and function of olfactory neurons in C. elegans; studies the initiation and progression of astrocytomas; studies the mechanism of cell division, animal cell motility and cell form; studies the structure and function of calcium-binding proteins (CaBPs) using NMR and computational methods; studies protein folding and protein structure prediction using computer models; studies the role and assembly of actin filaments, primarily in yeast and several more. This session discusses more about current research in cell and molecular biology.
Molecular biology concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, and proteins and their biosynthesis, as well as the regulation of these interactions. Molecular Biology is an approach from the viewpoint of the so-called basic sciences with the leading idea of searching below the large-scale manifestations of classical biology for the corresponding molecular plan. It is concerned particularly with the forms of biological molecules and is predominantly three-dimensional and structural, but not a refinement of morphology. Rather it delves into genesis and function. This session discusses more about micro biology and its impact on treating diseases.
Computational biology deals with the study, development and application of data-analytical and theoretical methods; mathematical modeling and computational simulation techniques in relation to the study of biological, behavioral, and social systems. It is an amalgamation of fields such as computer science, applied mathematics, animation, statistics, biochemistry, chemistry, biophysics, molecular biology, genetics, genomics, ecology, evolution, anatomy, and neuroscience. Computational biology is different from biological computation is a subfield of computer science and computer engineering using bioengineering and biology to build computers. This session discusses more about computational biology and its applications in developing treatment interventions to various serious diseases.
Drug design is the inventive process of finding new medications based on the knowledge of biological targets. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. Drug design is the design of a molecule that will bind tightly to its target. Finally drug design that relies on the knowledge of the three-dimensional structure of the biomolecular target is known as structure-based drug design. In addition to small molecules, biopharmaceuticals and especially therapeutic antibodies are an increasingly important class of drugs. This session discusses more about drug design and its safe and efficacious drug.
Cellular and molecular biology have contributed a lot to our lives in a number of ways impacting research, development of drugs to how cell works and its influence on medicine, biochemistry, virology, immunology, pharmacology, and several other areas such as high-tech industries such as agriculture to space programs etc. This session discusses in detail about cellular molecular biology and how greatly its impact on human lives.
Plant molecular biology is the study of the molecular basis of plant life. It is particularly concerned with the processes by which the information encoded in the genome is manifested as structures, processes and behaviors. Plant molecular biology has contributed a lot to genetics and biochemistry. It ushered a new era in research with the sequencing of the first plant genome in 2000. The discipline of plant molecular biology uses genetic, genomic, biochemical, cell biological and computational approaches to understand plant growth, physiology, and development at a molecular level. This session discusses more plant molecular biology and the advances it made in research and development
Molecular medicine is a new scientific discipline where physical, chemical, biological, bioinformatics and medical techniques are used to describe molecular structures and mechanisms, identify fundamental molecular and genetic errors of disease, and to develop molecular interventions to correct them. The molecular medicine perspective emphasizes cellular and molecular phenomena and interventions rather than the previous conceptual and observational focus on patients and their organs. This session discusses how molecular medicine has made rapid advances in research and development of medicines to diseases.
The Genetic Engineering is additionally called as hereditary alteration. It is the immediate control of a living beings of the genome by utilizing it . Qualities might be evacuated, or "thumped out", utilizing a nuclease. Quality is focusing on an alternate method that utilizations homologous recombination to change an endogenous quality, and this can be utilized to erase a quality, expel exons, include a quality, or to present hereditary transformations. It is an arrangement of advances used to change the hereditary cosmetics of the cell and including the exchange of qualities crosswise over species limits to create enhanced novel life forms. Hereditary designing does not regularly incorporate customary creature and plant rearing, in vitro treatment, acceptance of polyploidy, mutagenesis and cell combination systems that don't utilize recombinant nucleic acids or a hereditarily altered life form all the while.
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extra chromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA, which then may undergo error-prone repair or cause an error during other forms of repair, or else may cause an error during replication translation synthesis. Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics phenotype of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including functional diversity. The genomes of RNA viruses are based on RNA rather than DNA. The RNA viral genome can be double stranded DNA or single stranded. In some of these viruses such as the single stranded human immunodeficiency virus replication occurs quickly and there are no mechanisms to check the genome for accuracy.
Hematopoietic stem cell transplantation is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. It may be autologous the patient's own stem cells are used, allogeneic the stem cells come from a donor or syngeneic from an identical twin. It is a medical procedure in the field of hematology, most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic .
Hematopoietic stem cell transplantation remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer, such as autoimmune diseases and hereditary skeletal dysplasia’s notably malignant infantile osteoporosis and mucopolysaccharidosis.
Cell therapy incorporates a treatment in which cell fabric is imbued into a living cell. It refers to the cell alterations at the molecular level. If the chemotherapy in oncology for occurrence is considered, it implies to kill the cell by passing on harmful administrators to the cell, while Molecular medications would come to a conclusion over the cell division without basically butchering the cell. Gene therapy is a special strategy utilized in restorative treatment those employments particular sorts of genes to treat a few sorts of infections. Gene therapy is the one in which most endless researches are being carried out by analysts all over the world in order to avoid or treat few illnesses such as immune deficiencies, molecular biology of irresistible illnesses, cancer, and indeed HIV, through distinctive methodologies. Gene therapy is also utilized to treat a few innate infections, wherein the transformed imperfect gene is supplanted with the utilitarian gene.
Biochemistry deals with the structure and work of various biological molecules such as proteins, nucleic acids, carbohydrates and lipids and also the chemical and physic-physical process occurring with living organisms. It is moreover utilized to depict methods suitable for understanding the intuitive and capacities of biological molecules and it is a research facility based science that brings together science and chemistry. By utilizing chemical information and strategies, organic chemists can get it and unravel biological issues. Biochemistry centers on forms happening at a molecular level and it centres on what’s happening inside our cells. It too looks at how cells communicate with each other, for case amid cell development or battling sickness.
Microbiology deals with the study of living micro-organisms, which includes unicellular (single cell), multicellular (cell colony) organisms such as bacteria, virus, fungi, etc. Microbiology includes various sub disciplines counting virology, parasitology, mycology and bacteriology. Eukaryotic microorganisms have membrane-bound cell organelles and incorporate fungi, while prokaryotic life forms lack the membrane-bound cell organelles. The Microbiologists customarily depend on culture, staining, and microscopy. It is regularly based on molecular science devices such as DNA arrangement based identification, illustration 16s rRNA gene grouping utilized for microbes identification. Molecular genetics is the field of science that thinks about the structure and work of genes at molecular level and in this way utilizes strategies of both molecular science and genetics. This is valuable in the pondering of formative science and in understanding and treating genetic illnesses.
Stem cells are cells originate in all multi-cellular organisms. They were isolated in mice in 1981 and in humans in 1998. In humans there are several types of stem cells, each with variable levels of potency. Stem cell treatments are a type of cell therapy that introduces new cells into adult bodies for possible treatment of cancer, diabetes, neurological disorders and other medical conditions. Stem cells have been used to repair tissue damaged by disease or age. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.
Embryonic Stem Cells
Mesenchymal Stem Cells
Regulation of Stem Cells
Dedifferentiation, transdifferentiation and reprogramming
Stem Cells in Disease Modeling and Therapy
Stem Cell Treatments
Stem Cell Transplant
Stem Cell Technologies
Cancer Stem Cells
Stem Cells: Controversies & Regulation
Many of us might have observed that the tail of a lizard, if cut, can grow efficiently all over again. This is an example of tissue regeneration. Like lizards, in many other animals including humans tissue regrowth can be observed. By definition it means regrowth of damaged or affected tissue from rest of the part. The initial step is rearrangement of pre-existing tissue followed by de-differentiation and trans-differentiation of the cells. This involves cells called stem cells which have the potential to regenerate themselves. There are intrinsic signals that activate stem cells to undergo regeneration when needed. There are amazing instances of tissue regeneration, for example heart regeneration in zebra fish. In humans, liver cells can regenerate themselves. But there are many cells and tissue that lack this ability. To help humans fight tissue damages in a better way tissue regeneration needs immediate attention. Researchers across the globe should come together to unleash the mystery of the signals and genetics that trigger regeneration in some tissues.
Animal models of tissue regeneration
Molecular fundamentals of regeneration
Intrinsic Tissue regeneration
Guided Tissue Regeneration
Human tissue regeneration: Challenges in in-vivo and in-vitro regeneration
In silico Tissue engineering
Plant biotechnology is characterized as the utilization of learning acquired from investigation of the life sciences to make technological upgrades in plant species. Plant biotechnology has been led for more than ten thousand years. The underlying foundations of plant biotechnology can be followed back to the time when people began gathering seeds from their most wild plants and started cultivating them in tended fields. It appears that when the plants were cultivated, the seeds of the most attractive plants were held and replanted the next growing season. While these primitive agriculturists did not have knowledge of the life sciences, they apparently understood the fundamental standards of gathering and replanting the seeds of any normally happening variation plants with enhanced qualities, for example, those with the biggest fruits or the most elevated yield, in a procedure that we call artificial selection. This domestication and controlled change of plant species was the beginning of plant biotechnology.
Agriculture biotechnology, otherwise called agritech, is a territory of agrarian science including the utilization of logical scientific tools and methods, including genetic engineering, Bio markers, Vaccines, antibodies, and tissue culture, to modify living organisms: plants, animals, and microorganisms. In view of a comprehension of DNA, researchers have created answers for increase agriculture productivity. Beginning from the capacity to identify qualities that may confer points on specific harvests, and the capacity to work with such attributes exactly, biotechnology upgrades reproducers' ability to make enhancements in plants and animals.